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  • Course Information
    • Course Title Code Semester Laboratory+Practice (Hour) Pool Type ECTS
    DNA Repair BİY330 SPRING 3+0 E 5
    Learning Outcomes
    1-Defines the concept of mutation.
    2-Categorizes the causes of mutations
    3-Summarizes the responses of organisms to mutations.
    4-Compares diseases associated with mutations.
    Prerequisites -
    Language of Instruction Turkish
    Responsible Asst.Prof.Dr. Filiz SARIKAYA PEKACAR
    Instructors -
    Assistants -
    Resources R1. Alberts B., Johnson A.(2008). Hücrenin Moleküler Biyolojisi. (Dördüncü baskı). Tüba, Ankara. R2. Brown T.A. (2006). Genomes 3. (3rd Edition). Garland Science Taylor&Francis Group, New York.
    Supplementary Book SR1. Errol C.F., Graham C.W. vd. (2006). DNA Repair and Mutagenesis. (Second Edition). ASM Press, Washington D.C.
    Goals To teach the sources of DNA damage and the number and diversity of repair systems.
    Content DNA structure, nuclear DNA and mitochondrial DNA Mutations Reasons of spontaneous mutation Induced mutations Physical agents Chemical agents Biological agents Repair mechanisms Direct repair systems-nucleotide excision repair system Multi-step repair systems: Base Extraction Repair System Double strand break repair: SOS system and GO system DNA methylation and mismatch repair DNA repair and cancer relation DNA repair DNA repair and aging relation DNA repair and apoptosis DNA repair and related diseases DNA repair and mechanism of related diseases
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