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Week
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Topics
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Study Metarials
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1
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Determination of oxidation states in organic chemistry (Alkanes, alkenes and other functional groups)
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R1: Chapter 2
R3: Chapter 18
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2
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Introduction of oxidation and reduction agents
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R2: Chapter 3 and 4
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3
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Reduction of cycloalkanes(cyclopropane), alkynes and alkenes
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R2: Chapter 4
R4: Chapter 2
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4
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Reduction of aldehyde, ketones
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R2: Chapter 4
R4: Chapter 2
R6: Chapter 14
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5
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Reduction of carboxylic acids and their derivatives (acyl chlorides, anhydrides, esters, amides, nitriles)
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R2 Chapter 4
K4: Chapter 2
R6: Chapter 14
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6
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Reduction of nitrogen compounds, haloalkanes
acetals and ketals
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R2: Chapter 4
R4: Chapter 2
R6: Chapter 14
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7
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Oxidation of alcohols to carbonyls with Chrominum (VI), dimethyl sulfoxide, Dess-Martin, oppenauer, manganese dioxide, silver oxide and metal oxidants
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R2: Chapter 3
R5: Chapter 7
R6: Chapter 14
R7: Chapter 6
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8
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Formation of Phenols and Quinones
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R2: Chapter 3
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9
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Convertion of alkenes to epoxides (Epoxides from halohydrins, Sharpless asymmetric epoxidation)
Oxidative Bond Cleavage (cleavage of alkenes with transition metals and ozone)
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R2: Chapter 3
R4: Chapter 2
R7: Chapter 6
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10
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Conversion of alkenes to diols (oxidation with potassium permanganate, osmium tetroxide, the Prevost reaction, hydroxylation of aromatic rings)
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R2: Chapter 3
R4: Chapter 2
R5: Chapter 7
R7: Chapter 6
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11
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Oxidation of ketones: Baeyer-Villiger oxidation, peroxide oxidation, enzymatic Baeyer-Villiger oxidations
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R2: Chapter 3
R7: Chapter 6
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12
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Oxidation of alkyl or alkenyl fragments (Oxidation with selenium dioxide and chromium trioxide)
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R2: Chapter 3
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13
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Oxidation of sulfur, selenium and nitrogen compounds
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R2: Chapter 3
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14
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Oxidation and Reduction reactions in Synthesis
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R3: Chapter 18, SB1
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Prerequisites
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-
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Language of Instruction
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Turkish
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Responsible
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Prof. Dr. Zeynep GÜLTEKİN
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Instructors
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-
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Assistants
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----
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Resources
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R1. Hoffman, R. (1997). Organik Chemistry, Oxford University Press,
ISBN 0-19-509618-5.
R2. Smith, M.B. (1994). Organic Synthesis, McGraw-Hill, Inc.,
ISBN 0-07-048716-2.
R3. Hendrickson, J. B.; Cram, D .J.; Hammond, G.S. (1959). Organic Chemistry,
Third edition. ISBN 07-028150-5
R4. Fuhrhop, J.; Penzlin., G. (1994). Organic Synthesis, ISBN 3-527-29074-5.R
5. Bruice, P.Y. 1995. Organic Chemistry, Fifth Edition (Pearson Education, Inc.)
ISBN 3-13-199631-2
R6. Brückner R. (1996). Reactionsmechanismen., Berlin, Oxford.Spectrum.
Akad.Verl. ISBN 3-86025-363-8
R7. Carruthers W. (1986). Some modern methods of organic synthesis, Third
edition. Cambridge University Press, ISBN 052132234 0
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Supplementary Book
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SB1. March , J. (1992). Advance Organic Chemistry, John Wiley&Sons, Inc, ISBN 0-471-60180-2.
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Goals
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Gaining advanced knowledge about reduction and oxidation reactions in organic chemistry
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Content
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Determination of oxidation and reduction state of organic compounds. Reduction of cycloalkanes, alkynes, alkenes haloalkanes, nitrogen compounds, haloalkanes, aldehyde, ketones, heteroatom functional groups, carboxylic acids and their derivatives. Oxidation of alcohols to carbonyl. Conversion of alkenes to diols and epoxides. Oxidation of sulfur, selennium, and nitrogen. Oxidation of ketones. Oxidation of alkyl or alkenyl fragments.
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Program Learning Outcomes |
Level of Contribution |
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1
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Has the necessary theoretical and applied basic knowledge within the scope of natural science. Has the knowledge to evaluate the nature, source, limits, accuracy, reliability, and validity of the information.
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4
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2
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Participates in interdisciplinary studies by using the basic knowledge of the field and analytical thinking ability.
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-
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3
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Evaluates concepts, ideas, and data in the field of chemistry with scientific methods, identify and analyze complex problems and issues, make discussions, and develop suggestions based on evidence and research.
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-
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4
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Has the ability to design and implement experiments, use modern technical devices, collect data and analyze results in order to research and solve problems related to the field.
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-
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5
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Produces solutions by taking responsibility for solving unpredictable complex situations in applications in the field of chemistry.
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4
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6
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Informs periodically the people and institutions it is responsible for while conducting studies related to its field, and expresses its findings and suggestions for solutions to emerging problems in written, oral, and, if necessary, visual presentation.
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4
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7
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Determines the theoretical and practical deficiencies related to the field and directs the future learning processes.
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-
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8
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Has the knowledge of a foreign language at a level to be able to access the scientific information needs from foreign sources related to the field, update knowledge, and communicate with colleagues around the world.
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3
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9
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Uses computer software, information, and communication technologies at the level required by the field and accesses scientific resources in this way.
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-
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10
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Develops strategy, policy, and implementation plans on issues related to the field and manages the data obtained within the framework of quality processes.
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-
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11
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Supervises and checks the social, scientific, cultural, and ethical values at the stages of collection, interpretation, application, and announcement of the data related to the field.
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-
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