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Week
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Topics
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Study Metarials
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1
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Applied Enzymology
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R1: Chapter 1
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2
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Determination of Therapeutic Enzymes
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R1: Chapter 3
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3
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Enzymes for Treatment of Cardiovascular Diseases
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R1: Chapter 4
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4
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Oncolytic Enzymes
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R2: Chapter 6
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5
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New Enzymes for Treatment of Cancer
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R2: Chapter 7
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6
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Enzymes as Digestive Aids
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R2: Chapter 8
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7
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Enzymes to Treat Lysosomal Storage Diseases
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R2: Chapter 10
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8
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Carbonic anhydrase isoenzymes
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R2: Chapter 11
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9
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Enzymes for Treatment of Diabetes mellitus
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R3: Chapter 2
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10
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Enzymes with therapeutic potential in Alzheimer disease
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R3: Chapter 5
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11
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Hyaluronidases
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R3: Chapter 7
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12
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Oral and Inhalable Enzyme Therapies
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R3: Chapter 8
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13
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Enzymes in Infectious Diseases
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R1: Chapter 10
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14
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Other Therapeutic Enzymes
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R2: Chapter 15
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Prerequisites
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-
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Language of Instruction
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Turkish
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Responsible
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Assoc. Dr. Şevki ADEM
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Instructors
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1-)Profesör Dr. Şevki Adem
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Assistants
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Assoc. Dr. Şevki ADEM
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Resources
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R1. Barry M. McGrath, Gary Walsh, (2005). Directory of Therapeutic Enzymes, CRC Press, ISBN 9780849327148
R2. Chuang Lu, Albert P. Li, (2010). Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad Year: Wiley & Sons, ISBN:9780470281741
R3. Robert A. Copeland, (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists, Wiley & Sons, ISBN:9781118540398
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Supplementary Book
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-
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Goals
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Explain with examples what therapeutic enzymes are and how these enzymes are determined. At the same time, to obtain basic information about the mechanisms of these enzymes.
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Content
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What is a therapeutic enzyme, its importance in the treatment of diseases, therapeutic enzymes of some diseases such as cancer, Diabetes mellitus, Lysosomal Storage Diseases (LSD), Cardiovascular, etc.?
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Program Learning Outcomes |
Level of Contribution |
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1
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Develops, deepens and analyzes, and interprets the knowledge and skills at the master`s level at the level of expertise in the same field.
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3
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2
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Specializes in using and developing modern tools and equipment related to the field.
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-
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3
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Interprets and creates new ideas by synthesizing the knowledge gained in the field with the knowledge from other disciplines.
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3
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4
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Presents the current developments in the field and the research results with quantitative and qualitative data to the groups in the field and outside the field in a detailed and systematic way, in written, oral - visual form.
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-
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5
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Analyzes a problem in the field independently, develops a solution method, evaluates the results, and applies them when necessary.
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-
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6
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Has advanced oral and written communication skills in at least one foreign language.
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-
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7
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Performs a comprehensive study that puts a new face to science and technology, develops a scientific method and/or technological product/process, or applies a known method to a new field.
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3
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8
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Has the ability to do advanced resource research, and access databases and other information resources in order to access information related to the field.
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-
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9
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Conducts leadership in identifying and solving unique and interdisciplinary problems related to the field.
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3
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10
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Expands the boundaries of knowledge in its field by publishing at least one scientific article related to the field in international peer-reviewed journals.
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-
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11
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Evaluates the scientific, technological, social and cultural improvements and to transfer the knowledge to society objectively with ethical responsibility.
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-
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