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Week
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Topics
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Study Metarials
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1
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Definition and importance of organic chemistry, chemical bonds, okted rule, writing Lewis structures, formal charge, chemical formulas, functional groups.
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R1 Chapter 1 ve 2
R2 Chapter 1 ve 2
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2
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Atomic and molecular orbitals, hybrid orbitals of carbon (SP, SP2,SP3 hybridization), molecular geometry (VSEPR model), acids and bases (Lowry-Bronsted / Lewis acid-base concepts ), intermolecular interactions (dipole-dipole, hydrogen bonding).
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R1 Chapter 1 ve 3
R2 Chapter 1 ve 2
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3
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Basic reaction types in organic chemistry;
Substitution, addition, elimination, arrangements
reactions, reduction-oxidation reactions.
homolysis and heterolysis of covalent bonds, carbocathions and carbanions, the use of curved arrows in the representation of reactions. The concept of resonance.
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R1 Chapter 3, 6,7,8,11, 12, 16
R2 Chapter 2, 5,10, 13
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4
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Alkanes and cycloalkanes;
Nomenclature of alkanes, cycloalkanes and bicyclic alkanes, structure formulas, physical properties, usage areas. Synthesis and reactions of alkanes
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R1 Chapter 4
R2 Chapter 3
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5
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Alkenes ;
Nomenclature of alkenes, physical properties, stability and synthesis
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R1 Chapter 7
R2 Chapter 10
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6
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Addition reaction of alkenes:
Addition of water and sulfuric acid to alkenes, addition of water using mercury (II)acetate, addition of borane, halogen, HX, hydrogen, carbene to alkenes. Epoxidation of alkenes, oxidation of alkenes (syn hydroxylation)
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R1 Chapter 8
R2 Chapter 10
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7
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Alkynes;
The nomenclature, synthesis, acidity of alkynes.
Reactions of alkynes; hydrogen, halogen, HX, water addition. Oxidation of alkynes.
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R1 Chapter 7 ve 8
R2 Chapter 10
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8
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Stereochemistry: isomer types (constitutional and stereoisomers), conformation isomer of alkanes and cycloalkanes, the relative stabilities of cycloalkanes, Cis-Trans isomerism of cycloalkanes, geometric isomerism of alkene and cyclic compounds, E/Z system.
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R1 Chapter 4
R2 Chapter 4
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9
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Stereochemistry: isomer types (constitutional and stereoisomers), conformation isomer of alkanes and cycloalkanes, the relative stabilities of cycloalkanes, Cis-Trans isomerism of cycloalkanes, geometric isomerism of alkene and cyclic compounds, E/Z system.
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R1 Chapter 4
R2 Chapter 4
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10
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Stereochemistry: continued
The biological significance of chirality, determination of chirality, nomenclature of enantiomer : The R/S system, properties of enantiomers: optical activity and racemic mixtures, D,L system, chiral drugs.
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R1 Chapter 5
R2 Chapter 4
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11
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Stereochemistry: continued
Molecules with more than one stereogenic center, enantiomers, Diasteromers and Meso compounds, Fischer projection formulas, stereoisomerism of cyclic compounds, resolution of racemic mixtures, other asymmetric chiral molecules.
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R1 Chapter 5
R2 Chapter 4
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12
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Alkyl Halides;
Structure and importance, physical properties, classification and nomenclature of alkyl halides, nucleophilic substitution reactions (SN1, SN2), arrangements reactions in SN1 reactions.
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R1 Chapter 6
R2 Chapter 5
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13
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Alkyl Halides-continued
Elimination (E1, E2) reaction of alkyl halides.
Factors affecting substitution and elimination Reactions, Synthesis of other compounds from alkyl halides. Preparation of alkyl halides.
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R1 Chapter 6
R2 Chapter 5
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14
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Alcohols;
Structure , nomenclature, classification, basicity and acidity of alcohols, synthesis and reactions of alcohols
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R1 Chapter 11
R2 Chapter 7
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Prerequisites
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-
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Language of Instruction
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Turkish
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Responsible
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Öğr. Gör. Dr. Ali Rıza TÜFEKÇİ
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Instructors
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Assistants
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-
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Resources
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R1. Solomons, T.W.G.; Fryhle C. B. (2002). Organik Kimya (Yedinci basımdan çeviri,
Literatür yayıncılık. (Çeviri: Okay, G.; Yıldırır, Y),
ISBN 975-8431-87-0
R2. Fessenden, R. J.; Fessenden, J. S.; Marshall, W. Logue , 2001. Organik Kimya,
(Çeviri Editörü: Uyar, T). ISBN: 975-8531-01-8
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Supplementary Book
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-
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Goals
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The aim of this course is to draw Lewis structures and geometric shapes of organic molecules, drawing open structure of important functional groups in organic chemistry, nomenclature of alkanes, alkenes, alkynes, alcohols, and alkyl halides, their physical properties, synthesis and reactions of alkanes, alkenes, alkynes, alcohols, and alkyl halides, three dimensional structures of organic molecules, chirality and optical activity of organic molecules and its importance in pharmaceutical chemistry.
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Content
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Definition and importance of organic chemistry, Lewis structures of organic molecules, hybridization and geometric shapes, chemical bonds, basic reaction types, nomenclature of alkanes, alkenes, alkyne, alkyl halides and alcohols, their reactions and preparations. Functional groups and stereochemistry.
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Program Learning Outcomes |
Level of Contribution |
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1
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Has the necessary theoretical and applied basic knowledge in the basic fields of chemistry.
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3
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2
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Designs experiments and develops solution methods for research and problems related to chemistry, solve problems using appropriate analytical methods and techniques, collects data, and analyzes and interprets the results.
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-
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3
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Has the ability to use library facilities, written and online information resources to access up-to-date theoretical and practical information about chemistry.
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-
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4
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Follows the current developments in the field of science and technology, improves their knowledge, conducts an examination using scientific methods and techniques, and independently conducts advanced work related to their field.
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-
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5
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Participates in interdisciplinary studies by using basic knowledge and analytical thinking ability.
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-
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6
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Adapts theoretical and practical information to conditions to develop realistic solutions and strategies in scientific terms.
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-
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7
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Plans and manages activities for the professional development of employees in the chemical-related sectors under his responsibility.
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-
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8
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Takes responsibility for lifelong learning and teaching, follows current developments in chemistry and related fields, and constantly renews itself.
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3
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9
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Has a level of foreign language knowledge that will be able to access the scientific information needs from foreign sources related to his field, update knowledge, and communicate with colleagues around the world.
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-
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10
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Uses information and communication technologies along with computer software at the level required by the field for molecular modeling and chemical calculations.
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2
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11
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Informs the relevant persons and institutions on chemistry-related issues, and expresses his thoughts, and suggestions for solutions to problems, using effective written or oral communication in Turkish.
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-
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12
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Uses knowledge about the field of chemistry in the profession and daily life with the awareness of social responsibility.
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-
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13
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Has awareness of scientific and social rules and cultural and ethical values to carry out teamwork effectively and safely, as well as the technical rules that must be followed while conducting studies in its field.
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-
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14
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Uses related knowledge on human health and environmental consciousness for the benefit of the society.
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3
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