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Week
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Topics
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Study Metarials
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1
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Applied Enzymology
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R1: Chapter 1
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2
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Determination of Therapeutic Enzymes
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R1: Chapter 3
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3
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Enzymes for Treatment of Cardiovascular Diseases
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R1: Chapter 4
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4
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Oncolytic Enzymes
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R2: Chapter 6
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5
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New Enzymes for Treatment of Cancer
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R2: Chapter 7
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6
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Enzymes as Digestive Aids
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R2: Chapter 8
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7
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Enzymes to Treat Lysosomal Storage Diseases
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R2: Chapter 10
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8
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Carbonic anhydrase isoenzymes
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R2: Chapter 11
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9
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Enzymes for Treatment of Diabetes mellitus
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R3: Chapter 2
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10
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Enzymes with therapeutic potential in Alzheimer disease
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R3: Chapter 5
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11
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Hyaluronidases
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R3: Chapter 7
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12
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Oral and Inhalable Enzyme Therapies
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R3: Chapter 8
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13
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Enzymes in Infectious Diseases
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R1: Chapter 10
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14
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Other Therapeutic Enzymes
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R2: Chapter 15
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Prerequisites
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-
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Language of Instruction
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Turkish
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Responsible
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Assoc. Dr. Şevki ADEM
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Instructors
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1-)Profesör Dr. Şevki Adem
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Assistants
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Assoc. Dr. Şevki ADEM
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Resources
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R1. Barry M. McGrath, Gary Walsh, Directory of Therapeutic Enzymes, CRC Press, ISBN 9780849327148
R2. Chuang Lu, Albert P. Li, Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad Year: 2010,Wiley & Sons, ISBN:9780470281741
R3. Robert A. Copeland, Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists, Year:2013,Wiley & Sons, ISBN:9781118540398
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Supplementary Book
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-
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Goals
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Explain with examples what therapeutic enzymes are and how these enzymes are determined. At the same time, to obtain basic information about the mechanisms of these enzymes.
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Content
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What is a therapeutic enzyme, its importance in the treatment of diseases, therapeutic enzymes of some diseases such as cancer, Diabetes mellitus, Lysosomal Storage Diseases (LSD), Cardiovascular, etc.?
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Program Learning Outcomes |
Level of Contribution |
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1
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Based on the competencies of the doctorate, to develop and deepen the current and advanced knowledge in the field with original thinking and research at the level of expertise and to reach original definitions that will bring innovation to science.
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3
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2
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Understanding the interaction between the disciplines related to the field of chemistry; to achieve original results by using expertise in analyzing, synthesizing and evaluating new and complex ideas.
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-
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3
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To reach new scientific knowledge in the field of chemistry and to gain high level skills in research methods related to the field.
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4
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4
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To be able to develop a new scientific method in the field of chemistry or to apply a known method to a different problem.
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-
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5
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To be able to research, comprehend, design, adapt and apply an original subject.
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-
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6
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To be able to question, synthesize and evaluate new and complex ideas.
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3
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7
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Publishing original studies in peer-reviewed journals.
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-
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8
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To be able to develop original ideas and methods related to the field and interdisciplinary by using high level mental processes such as creative and questioning thinking, problem solving and decision making
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-
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9
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To be able to present their original views effectively in a professional community.
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3
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10
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To be able to communicate and discuss in at least one foreign language at an advanced level, written, oral and visual.
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-
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11
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To contribute to the process of becoming an information society by introducing technological advances in academic and professional contexts.
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-
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